DuraGen® Plus matrix

Limit uncertainty with the performance of the conformability offered by DuraGen® Plus matrix.

As one of the pioneers in regenerative collagen medicine and thanks to its Ultra Pure Collagen™ technology, Integra proposes Duraplasty Solution™ for natural dural regeneration and CSF leakages prevention.


  • Onlay graft: DuraGen® Plus matrix allows the graft to be used without sutures thanks to surface tension alone.
  • Conformability: DuraGen® Plus matrix conforms intimately with the complex surfaces of the brain and/or spinal cord.
  • Handling: the 30% increased in tensile strenght* allows DuraGen® Plus matrix to offer an easier handling during placement or repositionning.
  • Dedicated larger size: large graft of 12.5×17.5cm available for trauma cases and/or decompressive hemicraniectomies.
  • Adhesion Barrier: To inhibit post-surgical peridural fibrosis in procedures where nerve roots are exposed.

*vs. DuraGen® matrix, the 1st generation of Integra dural grafts.

Intended Use

DuraGen® Plus matrix is an absorbable implant designed for the repair and restoration of dural defects and as an adhesion barrier for the reduction of peridural fibrosis.

Regulatory and Legal information

INTEGRA LifeSciences Corporation
1100 Campus Road,
Princeton, New Jersey 08540 • USA

Integra LifeSciences Services (France) SAS
Immeuble Sequoia 2 • 97 allée Alexandre Borodine
Parc technologique de la Porte des Alpes
69800 Saint Priest • FRANCE
Phone: +33 (0)4 37 47 59 00 • fax: +33 (0)4 37 47 59 99

Availability of these products might vary from a given country or region to another, as a result of specific local regulatory approval or clearance requirements for sale in such country or region.

  • Non contractual document. The manufacturer reserves the right, without prior notice, to modify the products in order to improve their quality.
  • Warning: Applicable laws restrict these products to sale by or on the order of a physician.
  • Consult product labels and inserts for any indication, contraindications, hazards, warnings, precautions, and instructions for use.

Products mentioned in this document are CE class III devices. Please contact Integra customer service should you need any additional information on devices classification. All the medical devices mentioned on this document are CE marked in accordance with the applicable European laws, unless specifically identified as “NOT CE MARKED”. 

DuraGen is a registered trademark of Integra LifeSciences Corporation or its subsidiaries in the USA and/or other countries. Ultra Pure Collagen is a trademark of Integra LifeSciences Corporation or its subsidiaries in the United States and/or other countries.
©2022 Integra LifeSciences Corporation. All rights reserved.
Last modification date: 09/2022. 0472241-2-EN
Document for use in Europe, Middle-East & Africa only

For more information, please contact your Integra representative.
For complete product information, please consult product labels and inserts for any indications, contraindications, hazards, warnings, precautions, and instructions for use.