DuraGen® Secure matrix

Limit uncertainty with the enhanced contact assurance offered by DuraGen® Secure matrix. 

As one of the pioneers in regenerative collagen medicine, Integra proposes Duraplasty Solutions™ for natural dural regeneration and CSF leakages prevention.


  • Cellulose microlayer: The fluid activated cellulose microlayer associated with the conformability of DuraGen® Secure matrix allows to reinforce the contact at the dural margins.
  • Resist sideways movement: The DuraGen® Secure matrix’s hydrostatic attraction offers at least 6 times more slip resistance than traditional collagen only grafts1.
  • Stay in place: The DuraGen® Secure matrix’s hydrostatic attraction enables the graft to stay put at the dural margins even under repeated irrigation or prolonged immersion2.
  • Compromised dural margins: DuraGen® Secure matrix helps to restore the contact during cases involving compromised dural margins.

1. Report #PDTR-114 Slip Testing for Collagen Only Products, page 5, 2012.
2. Functional Performance (Standing Fluid or Resistance to Migration under Irrigation) of DuraGen® Secure in a Canine Durectomy Model. NAMSA GLP Protocol #11171; CEP# T11-4615 Approved 17-November 2011.

Intended Use

DuraGen Secure Dural Regeneration Matrix is an absorbable implant designed for the repair and restoration of dural defects in cranial and spinal surgical procedures.

Regulatory and Legal information

INTEGRA LifeSciences Corporation
1100 Campus Road,
Princeton, New Jersey 08540 • USA

Integra LifeSciences Services (France) SAS
Immeuble Sequoia 2 • 97 allée Alexandre Borodine
Parc technologique de la Porte des Alpes
69800 Saint Priest • FRANCE
Phone: +33 (0)4 37 47 59 00 • fax: +33 (0)4 37 47 59 99

Availability of these products might vary from a given country or region to another, as a result of specific local regulatory approval or clearance requirements for sale in such country or region.

  • Non contractual document. The manufacturer reserves the right, without prior notice, to modify the products in order to improve their quality.
  • Warning: Applicable laws restrict these products to sale by or on the order of a physician.
  • Consult product labels and inserts for any indication, contraindications, hazards, warnings, precautions, and instructions for use.

Products mentioned in this document are CE class IIa (Extended Tip Applicators) and III devices. Please contact Integra customer service should you need any additional information on devices classification. All the medical devices mentioned on this document are CE marked in accordance with the applicable European laws, unless specifically identified as “NOT CE MARKED”.

DuraGen is a trademark of Integra Lifesciences Corporation in the United States and/or other countries. Ultra Pure Collagen is a trademark of Integra LifeSciences Corporation or its subsidiaries in the United States and/or other countries. All rights reserved.
Last modification date: 09/2022. 0472248-2-EN
Document for use in Europe, Middle-East & Africa only.

For more information, please contact your Integra representative.
For complete product information, please consult product labels and inserts for any indications, contraindications, hazards, warnings, precautions, and instructions for use.